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TRT: Frequently Asked Questions

Answers to the most common questions about testosterone replacement therapy — safety, cost, timeline, fertility, and how to get started.

What is TRT?

Testosterone Replacement Therapy is a prescribed medical treatment that restores testosterone to normal physiological levels (450-700 ng/dL) in men diagnosed with hypogonadism. It is administered through injections, gels, patches, or pellets under ongoing medical supervision.

How do I know if I need TRT?

If you are experiencing persistent fatigue, low libido, difficulty building muscle, weight gain, brain fog, or mood changes, a blood test measuring total and free testosterone can determine if your levels are clinically low (below 300 ng/dL on two separate morning tests).

Is TRT safe?

The TRAVERSE trial (5,246 men) found no increased risk of heart attack, stroke, or prostate cancer with properly monitored TRT. In December 2025, an FDA expert panel recommended removing the prostate cancer warning from TRT labels.

How long does TRT take to work?

Most men notice energy and mood improvements within 3-6 weeks. Sexual function improves within 3-6 weeks. Body composition changes become visible over 3-6 months. Full optimization typically occurs by 9-12 months.

Does TRT affect fertility?

Yes. Exogenous testosterone suppresses sperm production. This is usually reversible after stopping, but recovery can take 6-12 months. If fertility matters, discuss alternatives like clomiphene or HCG co-therapy with your provider before starting.

How much does TRT cost?

Heyday offers TRT starting at $99/month on the annual plan. All plans include provider consultations, medication, supplies, shipping, lab monitoring, and dose adjustments. No hidden fees.

Can I get TRT online?

Yes. Licensed telehealth providers can prescribe TRT after reviewing comprehensive lab work and conducting a virtual consultation. Heyday serves patients in all 50 states.

What are the side effects of TRT?

The most common side effect is elevated red blood cells (polycythemia), occurring in 5-10% of patients. This is caught with regular CBC monitoring. Other possibilities include acne, fluid retention, and mood changes — all manageable with proper oversight.

Will I need TRT forever?

TRT is a long-term treatment. Exogenous testosterone suppresses natural production, so stopping typically results in levels dropping back to or below pre-treatment levels. Most men continue indefinitely.

What is the difference between TRT and steroids?

TRT restores testosterone to normal physiological levels (450-700 ng/dL) under medical supervision. Anabolic steroid use involves supraphysiological doses (2-10x normal) without medical oversight. The goals, doses, and risk profiles are fundamentally different.

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